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Safest Ultra Low Temperature Freezer: New site

Designing and building the safest ultra low temperature freezer was not an easy task. But we did it by taking into consideration relevant 'hands-on' experts' opinions. We ended up creating an actual solution for an actual problem: specimens like precious DNA samples can't be lost because of technical failure. Therefore, we built an easy to use machine with an amazing interface that will let you manager your inventory without even opening the door. This piece of equipment won't fail, because even if it fails your samples will remain protected. Yes, you heard it right: in our safest ultra low temperature freezer, the Twincore, if one compressor fails, the other one is capable of maintaining -82 degrees C by itself indefinitely. We are happy to announce the creation and launch of the new dedicated space for our beloved Twincore, the safest ultra low temperature freezer yet. There's so much to say about it  from any angle that every researcher or  lab owner will find amazing and unique features. For this reason we created its own web space. In it you will find its features and links to more specific topics and technical sheets download. If you feel that something is missing we would appreciate that you let us know so we can improve. Please feel free to send a line if you have any question. We will reply shortly. You can access it from our website or following this link. If you want to share it with somebody but don't have the link at hand, simply tell them to click on safestult.com and they will be redirected. Keep it cool! Z.    


New Technology v.s. Dinosaurian Technology

Originally posted by Z-SC1's CEO Jean Fallacara here. Jean is always open to discussion. Connect with him on Linked In here. Today, we have revolutionized our world with amazing technologies. We have reshaped the technology of the past's to make better products, offer more security and give peace of mind. The Stone Age is a broad prehistoric period during which stone was widely used to make implements with a sharp edge, at Z-SC1 we believe that cascade refrigeration systems is also a dinosaurian technology that some manufacturers just try to keep alive (or even reanimate) for obvious financial reason. Matter of fact, the cascade refrigeration technology poorly failed to offer security, and generated billions $ of losses over the last decades. Protection of valuable and oftentimes irreplaceable biospecimens is a critical factor for ensuring valid and reproducible pre-clinical drug development results. Too much damage to important specimens caused by malfunctioning equipment, too much continued vigilance to proper biological specimen storage is required. Due to the obvious divide set between cascade refrigeration and Dual Cooling single compressors, sometimes both generations are forced to meet which commonly results in conflicting ideologies of digital technology. The everyday regime of work life in Science is becoming more technologically advanced with improved computers in offices, more complicated machinery in industry etc. With technology moving so fast it is hard for some manufacturer to keep up. In fact, some things seem so strange to us that we immediately put them out of our minds as being completely wrong.... What the Scientific community think about this, how do you feel about Do you really believe that being Extremely paranoid about your samples inside ULT freezers shall be a justifiable reason You spreads samples across multiple freezers, as a hedge in case of failure.... I don't! ... in all these Research labs, biorepositories, Biobanks... What are You exactly expecting from US and from ALL manufacturers of ULT Freezers?. Definitely Not a sales speech... Only facts, and a simple thing: PEACE OF MINDfor the storage of their high-value samples!


TWINCORE ULT: Safest Ultra Low Temperature Freezer yet.

This is a 'one-pager' ad published in a magazine during August. We received various comments regarding the way we presented the information. It features the Pull-Up and Pull Down times as well as an energy efficiency graphics. TWINCORE ULT: Safest Ultra Low Temperature Freezer yet. Check the Twincore's page here. Here it is for you to enjoy.


DNA Evidence Testing: Jack the Ripper and Gregory Turner

Aaron Kosminski was identified as  Jack the Ripper by DNA evidence testing. Gregory Turner was bound for life in prison after an RCMP lab reported  a tiny amount of DNA on his gold ring from a murdered woman, but the lab was wrong. Is DNA evidence reliable? It definitely depends. One of the most difficult murder mysteries of all times is solved: the identity of Jack the Ripper. At least that's what an 'amateur sleuth' claims by presenting new DNA evidence from a shawl that was supposedly found at a crime scene 126 years ago. The piece of cloth had blood from the victim and semen from Jack. The investigation was held by Dr Jari Louhelainen in the UK. You can read different versions of this story: Mail Online, Smithsonian Mag. Mr. Turner was convicted to life in prison but he was very lucky to have Mr. Jerome Kennedy as a lawyer: "A lucky hunch by Mr. Kennedy - now Newfoundland's Minister of Health - saved Mr. Turner from a life behind bars. He sought the name and DNA profile of every technician who had worked at the RCMP lab. It turned out that the technician who had tested the ring had also been working on the victim's fingernails a few inches away, creating a strong possibility of contamination." The tester had accidentally contaminated samples in other cases too. Mr. Turner's spent 27 months in jail. Read his story here from The Globe and Mail. DNA evidence depends on many factors but its manipulation and environment may risk its stability. We are no experts in crime scene investigation. If you want to learn a bit about Collection and Preservation of Blood Evidence from Crime Scenes, click here. If you want interesting technology, science and art content, come back soon! Check out this video about the DNA investigation that led to Ripper's identity.  


When Ultra Low Temperature becomes Extreme Low Temperature

Ultra low temperatures. We're just amazed with this universe that is unveiled when we go down the thermometer. Unimaginable processes are possible as predicted by science fiction or really, really smart scientists. In this case, we want to share one of our favorite 'cold' stories about Erick Cornell, Nobel Prize Laureate: "The Nobel Prize in Physics 2001 was awarded jointly to Eric A. Cornell, Wolfgang Ketterle and Carl E. Wieman "for the achievement of Bose-Einstein condensation in dilute gases of alkali atoms, and for early fundamental studies of the properties of the condensates"." The video we are sharing, explained by Cornell himself, illustrates how to achieve the Bose-Einstein condensation, a state of matter in which a diluted gas is brought down near absolute zero. At this point, Quantum effects become apparent. The 'Quantum-world' is of great interest in our everyday life as it is the key to a major leap in computer technology. By implementing Quantum computation, big problems that would take years (that's right, years) to compute in today's machines will be solved in a matter of seconds. If you want more detailed information about this issue, we recommend this Ted Talk video featuring Michelle Simmons at Tedx Sydney. We hope quantum technology arrives in the near future. But for now, we will continue keeping our stable Ultra Low Temperatures..... ultra low. The video is presented by the National Institute of Standards and Technology. We hope you enjoy it.


THERAPEUTIC HYPOTHERMIA: EMBRACING COLD

Heart attack's main risk involves permanent brain damage which is produced by the lack of oxygen to the organ . Many victims wake up looking normal but their brains will never be the same. This interesting story published at The Daily Mail details  the recovery of Mike Burton after the attack. In recent years, cardiologists all over the world have adopted the therapeutic hypothermia treatment which uses "the simplest of technologies: ice" as stated by The Wall Street Journal. The procedure, as described in the article affirms that  "Once a patient's heartbeat is restored, emergency-room doctors, cardiologists and rescue squads are quickly applying ice and other coolants to moderately lower a patient's body temperature by about six degrees. Then the patient is put in a drug-induced coma in intensive care for 24 hours before gradually being warmed back up to normal temperature." And because it's working, many ER facilities have been adopting this treatment, embracing the cold, as we do. We want to share a video from Penn Medicine's Center for Resuscitation Science in which they describe a successful experience with it. We hope you enjoy it.


Wood Frog: The Miracle of being frozen for a season

Many animals look for shelter to resist winter. The North American wood frog instead, embraces it and prepares its body to resist a season completely frozen. How do they do it? First, the frog draws water out of its cells to spaces where it would do less damage if it freezes. At the same time, its liver produces large amounts of sugar that act as anti-freeze. Then, the entire animal slowly freezes from the outside until its heart stops beating. When spring arises they come back to life! On the subject, Science Line says: "As the wood frog is freezing, its heart continues pumping the protective glucose around its body, but the frog’s heart slows and eventually stops. All other organs stop functioning. The frog doesn’t use oxygen and actually appears to be dead. In fact, if you opened up a frozen frog, the organs would look like “beef jerky” and the frozen water around the organs like a “snow cone,” says Jon Costanzo, a physiological ecologist at Miami University in Ohio who studies freeze-tolerance. Any ideas on how to use nature's freezing processes to make the world a better place? We would like to share a very interesting video hosted by David Attenborough about the North American wood frog: The Miracle of the Wood Frog. Enjoy! Image taken from ScienceMag.


Lengthen Transplant Window by Supercooling Organs

We like cold: we are based in Canada and manufacture a whole bunch of cooling and freezing equipment. At least, we embrace it! We are very happy to share this great story originally posted by IFLScience from a paper published in Nature Medicine about supercooling organs in order to lengthen the transplant window. To summarize, they excised livers from rats and cooled them down to 4C without completely freezing them to store later at -6C. After three days the livers were ready for transplant and recipients rats were alive for three months after the transplant. You see? Cold is actually, pretty cool! We invite you to read the original post here.


Artistic Images Made With Science Technology

Or are they plain scientific images? Definitely not plain. What would art be if not strongly paired with science? They are always catching with each other and providing us with stunning content. Technology is always helping scientist and artists push their boundaries. This time, we would like to present a couple of images (videos) made with confocal microscopy. Any resemblance with video art is pure coincidence. The first, a beautiful video showing the metaphase, probably the most recognizable phase of mitosis, thanks to the technology advances provided this time by Nikon. This images were made with a C1si/TE2000 laser scanning confocal microscopy and belong to Nikon's MicroscopyU. MITOSIS MICROSCOPIC VIDEO The second is a video animation created with a LEICA LAS AF 3 3D by Dr. Masahiro Fukuda, Prof. Haruo Kasai, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, The University of Tokyo, Tokyo, Japan: excitatory pyramidal neurons in Layer 5 partly express EYFP. Watch it here. Amazing products are there for people to thrive and created by companies that can understand those people.    


FROZEN: U.S. & CANADA – New Ultra Low Freezer Technology.

Z-SC1 invests $1.2M for the launch of its ULT Twincore Freezer.

Z-SC1 invests $1.2M for the launch of its revolutionary Twincore ULT Freezer in the US and Canada Market. Z-SC1 Corp announces today that it has secured new funding totaling $1.2M. The funding has been provided by a consortium of Share Holders, Investissement Québec & the bank Desjardins Affaires with insurance support from Export Development Canada. This new capital will be used by Z-SC1 in Marketing & Sales support to launch its revolutionary TWINCORE -86ºC ULT Freezer in North America. TwinCore© ultra-low freezers are designed for -86°C storage of high-value samples. Revolutionary Double Independent refrigeration systems offering unbeatable security and outstanding Integrity for your samples. TwinCore© Technology employs 2 optimized autocascade compressors. However it only requires one compressor to hold temperature up to -86. These ULT also have an advanced 7’’ LCD touch screen control panel, inventory management system and each unit is assigned an IP address for monitoring functions by the Z-Sc1 WIZBOX network. The TWINCORE can preserve integrity for research samples for almost 12H (world record) and has the fastest pull down in the industry, TwinCore ULT only requires about 3H to reach -82ºC. Z-SC1 Corp. is a Canadian-based international company with a successful record of developing laboratory equipment for the biomedical in North & South America. Z-SC1 is headquartered in Montreal, Canada with manufacturing bases in South-Korea   DESJARDINS AFFAIRES EXPORT DEVELOPMENT CANADA   INVESTISSEMENT QUEBEC


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